Mangosteen peel extract comes from the thick rind of the mangosteen fruit and is rich in xanthones, a class of polyphenols including alpha mangostin that are largely unique to this plant family.
Isolated xanthones from the pericarp are potent free radical scavengers in direct laboratory testing, and in human keratinocyte cell culture, alpha mangostin and related compounds have been shown to reduce UV and oxidative stress related damage and support cell viability.
All of this evidence sits at the isolated compound or cell culture level, and there is no well controlled human clinical trial demonstrating that topical mangosteen peel extract, as formulated in a finished cosmetic product, produces a measurable antioxidant or anti aging outcome in living human skin.
Mangosteen Peel Extract References
Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen)
Mangostanin, a Xanthone Derived from Garcinia mangostana Fruit, Exerts Protective and Reparative Effects on Oxidative Damage in Human Keratinocytes, 2022
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