Muhammad JunaidCoQ10 is unique among topical antioxidants in that skin cells can actually synthesize a small amount of it on their own, and the body has an enzymatic system specifically designed to regenerate it once it's been used up neutralizing free radicals, though that system's efficiency declines with age.
In its reduced form, called ubiquinol, CoQ10 also helps regenerate vitamin E after it's been oxidized, giving it a supporting role in the broader antioxidant network. Separately, research has shown CoQ10 can inhibit collagenase, an enzyme responsible for breaking down collagen, and reduce UVA-induced production of other metalloproteinases linked to wrinkle formation.
Coenzyme Q10 (Ubiquinone) References
Addor FAS. Antioxidants in dermatology. Anais Brasileiros de Dermatologia, 2017
Lain E, et al. "The Role of Coenzyme Q10 in Skin Aging and Opportunities for Topical Intervention: A Review" — Journal of Clinical and Aesthetic Dermatology, 2024 (PMC)
"The Usage of Coenzyme Q10 on Skin Aging: A Systematic Review on Animal and Clinical Study" — Scope Journal
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